N-glycosylation shields Phytophthora sojae apoplastic effector PsXEG1 from a specific host aspartic protease.
Identifieur interne : 000101 ( Main/Exploration ); précédent : 000100; suivant : 000102N-glycosylation shields Phytophthora sojae apoplastic effector PsXEG1 from a specific host aspartic protease.
Auteurs : Yeqiang Xia [République populaire de Chine] ; Zhenchuan Ma [République populaire de Chine] ; Min Qiu [République populaire de Chine] ; Baodian Guo [République populaire de Chine] ; Qi Zhang [République populaire de Chine] ; Haibin Jiang [République populaire de Chine] ; Baiyu Zhang [République populaire de Chine] ; Yachun Lin [République populaire de Chine] ; Mingrun Xuan [République populaire de Chine] ; Liang Sun [République populaire de Chine] ; Haidong Shu [République populaire de Chine] ; Junhua Xiao [République populaire de Chine] ; Wenwu Ye [République populaire de Chine] ; Yan Wang [République populaire de Chine] ; Yiming Wang [République populaire de Chine] ; Suomeng Dong [République populaire de Chine] ; Brett M. Tyler [États-Unis] ; Yuanchao Wang [République populaire de Chine]Source :
- Proceedings of the National Academy of Sciences of the United States of America [ 1091-6490 ] ; 2020.
Abstract
Hosts and pathogens are engaged in a continuous evolutionary struggle for physiological dominance. A major site of this struggle is the apoplast. In Phytophthora sojae-soybean interactions, PsXEG1, a pathogen-secreted apoplastic endoglucanase, is a key focal point of this struggle, and the subject of two layers of host defense and pathogen counterdefense. Here, we show that N-glycosylation of PsXEG1 represents an additional layer of this coevolutionary struggle, protecting PsXEG1 against a host apoplastic aspartic protease, GmAP5, that specifically targets PsXEG1. This posttranslational modification also attenuated binding by the previously described host inhibitor, GmGIP1. N-glycosylation of PsXEG1 at N174 and N190 inhibited binding and degradation by GmAP5 and was essential for PsXEG1's full virulence contribution, except in GmAP5-silenced soybeans. Silencing of GmAP5 reduced soybean resistance against WT P. sojae but not against PsXEG1 deletion strains of P. sojae. The crucial role of N-glycosylation within the three layers of defense and counterdefense centered on PsXEG1 highlight the critical importance of this conserved apoplastic effector and its posttranslational modification in Phytophthora-host coevolutionary conflict.
DOI: 10.1073/pnas.2012149117
PubMed: 33082226
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Chine</country><wicri:regionArea>Key Laboratory of Integrated Management of Crop Diseases and Pests (Ministry of Education), College of Plant Protection, Nanjing Agricultural University, Nanjing 210095</wicri:regionArea><wicri:noRegion>Nanjing 210095</wicri:noRegion></affiliation><affiliation wicri:level="1"><nlm:affiliation>The Key Laboratory of Plant Immunity, Nanjing Agricultural University, 210095 Nanjing, China.</nlm:affiliation><country xml:lang="fr">République populaire de Chine</country><wicri:regionArea>The Key Laboratory of Plant Immunity, Nanjing Agricultural University, 210095 Nanjing</wicri:regionArea><wicri:noRegion>210095 Nanjing</wicri:noRegion></affiliation></author><author><name sortKey="Guo, Baodian" sort="Guo, Baodian" uniqKey="Guo B" first="Baodian" last="Guo">Baodian Guo</name><affiliation wicri:level="1"><nlm:affiliation>Department of Plant Pathology, Nanjing Agricultural University, 210095 Nanjing, China.</nlm:affiliation><country xml:lang="fr">République populaire de Chine</country><wicri:regionArea>Department of Plant Pathology, Nanjing Agricultural University, 210095 Nanjing</wicri:regionArea><wicri:noRegion>210095 Nanjing</wicri:noRegion></affiliation><affiliation wicri:level="1"><nlm:affiliation>Key Laboratory of Integrated Management of Crop Diseases and Pests (Ministry of Education), College of Plant Protection, Nanjing Agricultural University, Nanjing 210095, China.</nlm:affiliation><country xml:lang="fr">République populaire de Chine</country><wicri:regionArea>Key Laboratory of Integrated Management of Crop Diseases and Pests (Ministry of Education), College of Plant Protection, Nanjing Agricultural University, Nanjing 210095</wicri:regionArea><wicri:noRegion>Nanjing 210095</wicri:noRegion></affiliation><affiliation wicri:level="1"><nlm:affiliation>The Key Laboratory of Plant Immunity, Nanjing Agricultural University, 210095 Nanjing, China.</nlm:affiliation><country xml:lang="fr">République populaire de Chine</country><wicri:regionArea>The Key Laboratory of Plant Immunity, Nanjing Agricultural University, 210095 Nanjing</wicri:regionArea><wicri:noRegion>210095 Nanjing</wicri:noRegion></affiliation></author><author><name sortKey="Zhang, Qi" sort="Zhang, Qi" uniqKey="Zhang Q" first="Qi" last="Zhang">Qi Zhang</name><affiliation wicri:level="1"><nlm:affiliation>Department of Plant Pathology, Nanjing Agricultural University, 210095 Nanjing, China.</nlm:affiliation><country xml:lang="fr">République populaire de Chine</country><wicri:regionArea>Department of Plant Pathology, Nanjing Agricultural University, 210095 Nanjing</wicri:regionArea><wicri:noRegion>210095 Nanjing</wicri:noRegion></affiliation><affiliation wicri:level="1"><nlm:affiliation>Key Laboratory of Integrated Management of Crop Diseases and Pests (Ministry of Education), College of Plant Protection, Nanjing Agricultural University, Nanjing 210095, China.</nlm:affiliation><country xml:lang="fr">République populaire de Chine</country><wicri:regionArea>Key Laboratory of Integrated Management of Crop Diseases and Pests (Ministry of Education), College of Plant Protection, Nanjing Agricultural University, Nanjing 210095</wicri:regionArea><wicri:noRegion>Nanjing 210095</wicri:noRegion></affiliation><affiliation wicri:level="1"><nlm:affiliation>The Key Laboratory of Plant Immunity, Nanjing Agricultural University, 210095 Nanjing, China.</nlm:affiliation><country xml:lang="fr">République populaire de Chine</country><wicri:regionArea>The Key Laboratory of Plant Immunity, Nanjing Agricultural University, 210095 Nanjing</wicri:regionArea><wicri:noRegion>210095 Nanjing</wicri:noRegion></affiliation></author><author><name sortKey="Jiang, Haibin" sort="Jiang, Haibin" uniqKey="Jiang H" first="Haibin" last="Jiang">Haibin Jiang</name><affiliation wicri:level="1"><nlm:affiliation>Department of Plant Pathology, Nanjing Agricultural University, 210095 Nanjing, China.</nlm:affiliation><country xml:lang="fr">République populaire de Chine</country><wicri:regionArea>Department of Plant Pathology, Nanjing Agricultural University, 210095 Nanjing</wicri:regionArea><wicri:noRegion>210095 Nanjing</wicri:noRegion></affiliation><affiliation wicri:level="1"><nlm:affiliation>Key Laboratory of Integrated Management of Crop Diseases and Pests (Ministry of Education), College of Plant Protection, Nanjing Agricultural University, Nanjing 210095, China.</nlm:affiliation><country xml:lang="fr">République populaire de Chine</country><wicri:regionArea>Key Laboratory of Integrated Management of Crop Diseases and Pests (Ministry of Education), College of Plant Protection, Nanjing Agricultural University, Nanjing 210095</wicri:regionArea><wicri:noRegion>Nanjing 210095</wicri:noRegion></affiliation><affiliation wicri:level="1"><nlm:affiliation>The Key Laboratory of Plant Immunity, Nanjing Agricultural University, 210095 Nanjing, China.</nlm:affiliation><country xml:lang="fr">République populaire de Chine</country><wicri:regionArea>The Key Laboratory of Plant Immunity, Nanjing Agricultural University, 210095 Nanjing</wicri:regionArea><wicri:noRegion>210095 Nanjing</wicri:noRegion></affiliation></author><author><name sortKey="Zhang, Baiyu" sort="Zhang, Baiyu" uniqKey="Zhang B" first="Baiyu" last="Zhang">Baiyu Zhang</name><affiliation wicri:level="1"><nlm:affiliation>Department of Plant Pathology, Nanjing Agricultural University, 210095 Nanjing, China.</nlm:affiliation><country xml:lang="fr">République populaire de Chine</country><wicri:regionArea>Department of Plant Pathology, Nanjing Agricultural University, 210095 Nanjing</wicri:regionArea><wicri:noRegion>210095 Nanjing</wicri:noRegion></affiliation><affiliation wicri:level="1"><nlm:affiliation>Key Laboratory of Integrated Management of Crop Diseases and Pests (Ministry of Education), College of Plant Protection, Nanjing Agricultural University, Nanjing 210095, China.</nlm:affiliation><country xml:lang="fr">République populaire de Chine</country><wicri:regionArea>Key Laboratory of Integrated Management of Crop Diseases and Pests (Ministry of Education), College of Plant Protection, Nanjing Agricultural University, Nanjing 210095</wicri:regionArea><wicri:noRegion>Nanjing 210095</wicri:noRegion></affiliation><affiliation wicri:level="1"><nlm:affiliation>The Key Laboratory of Plant Immunity, Nanjing Agricultural University, 210095 Nanjing, China.</nlm:affiliation><country xml:lang="fr">République populaire de Chine</country><wicri:regionArea>The Key Laboratory of Plant Immunity, Nanjing Agricultural University, 210095 Nanjing</wicri:regionArea><wicri:noRegion>210095 Nanjing</wicri:noRegion></affiliation></author><author><name sortKey="Lin, Yachun" sort="Lin, Yachun" uniqKey="Lin Y" first="Yachun" last="Lin">Yachun Lin</name><affiliation wicri:level="1"><nlm:affiliation>Department of Plant Pathology, Nanjing Agricultural University, 210095 Nanjing, China.</nlm:affiliation><country xml:lang="fr">République populaire de Chine</country><wicri:regionArea>Department of Plant Pathology, Nanjing Agricultural University, 210095 Nanjing</wicri:regionArea><wicri:noRegion>210095 Nanjing</wicri:noRegion></affiliation><affiliation wicri:level="1"><nlm:affiliation>Key Laboratory of Integrated Management of Crop Diseases and Pests (Ministry of Education), College of Plant Protection, Nanjing Agricultural University, Nanjing 210095, China.</nlm:affiliation><country xml:lang="fr">République populaire de Chine</country><wicri:regionArea>Key Laboratory of Integrated Management of Crop Diseases and Pests (Ministry of Education), College of Plant Protection, Nanjing Agricultural University, Nanjing 210095</wicri:regionArea><wicri:noRegion>Nanjing 210095</wicri:noRegion></affiliation><affiliation wicri:level="1"><nlm:affiliation>The Key Laboratory of Plant Immunity, Nanjing Agricultural University, 210095 Nanjing, China.</nlm:affiliation><country xml:lang="fr">République populaire de Chine</country><wicri:regionArea>The Key Laboratory of Plant Immunity, Nanjing Agricultural University, 210095 Nanjing</wicri:regionArea><wicri:noRegion>210095 Nanjing</wicri:noRegion></affiliation></author><author><name sortKey="Xuan, Mingrun" sort="Xuan, Mingrun" uniqKey="Xuan M" first="Mingrun" last="Xuan">Mingrun Xuan</name><affiliation wicri:level="1"><nlm:affiliation>Department of Plant Pathology, Nanjing Agricultural University, 210095 Nanjing, China.</nlm:affiliation><country xml:lang="fr">République populaire de Chine</country><wicri:regionArea>Department of Plant Pathology, Nanjing Agricultural University, 210095 Nanjing</wicri:regionArea><wicri:noRegion>210095 Nanjing</wicri:noRegion></affiliation><affiliation wicri:level="1"><nlm:affiliation>Key Laboratory of Integrated Management of Crop Diseases and Pests (Ministry of Education), College of Plant Protection, Nanjing Agricultural University, Nanjing 210095, China.</nlm:affiliation><country xml:lang="fr">République populaire de Chine</country><wicri:regionArea>Key Laboratory of Integrated Management of Crop Diseases and Pests (Ministry of Education), College of Plant Protection, Nanjing Agricultural University, Nanjing 210095</wicri:regionArea><wicri:noRegion>Nanjing 210095</wicri:noRegion></affiliation><affiliation wicri:level="1"><nlm:affiliation>The Key Laboratory of Plant Immunity, Nanjing Agricultural University, 210095 Nanjing, China.</nlm:affiliation><country xml:lang="fr">République populaire de Chine</country><wicri:regionArea>The Key Laboratory of Plant Immunity, Nanjing Agricultural University, 210095 Nanjing</wicri:regionArea><wicri:noRegion>210095 Nanjing</wicri:noRegion></affiliation></author><author><name sortKey="Sun, Liang" sort="Sun, Liang" uniqKey="Sun L" first="Liang" last="Sun">Liang Sun</name><affiliation wicri:level="1"><nlm:affiliation>Department of Plant Pathology, Nanjing Agricultural University, 210095 Nanjing, China.</nlm:affiliation><country xml:lang="fr">République populaire de Chine</country><wicri:regionArea>Department of Plant Pathology, Nanjing Agricultural University, 210095 Nanjing</wicri:regionArea><wicri:noRegion>210095 Nanjing</wicri:noRegion></affiliation><affiliation wicri:level="1"><nlm:affiliation>Key Laboratory of Integrated Management of Crop Diseases and Pests (Ministry of Education), College of Plant Protection, Nanjing Agricultural University, Nanjing 210095, China.</nlm:affiliation><country xml:lang="fr">République populaire de Chine</country><wicri:regionArea>Key Laboratory of Integrated Management of Crop Diseases and Pests (Ministry of Education), College of Plant Protection, Nanjing Agricultural University, Nanjing 210095</wicri:regionArea><wicri:noRegion>Nanjing 210095</wicri:noRegion></affiliation><affiliation wicri:level="1"><nlm:affiliation>The Key Laboratory of Plant Immunity, Nanjing Agricultural University, 210095 Nanjing, China.</nlm:affiliation><country xml:lang="fr">République populaire de Chine</country><wicri:regionArea>The Key Laboratory of Plant Immunity, Nanjing Agricultural University, 210095 Nanjing</wicri:regionArea><wicri:noRegion>210095 Nanjing</wicri:noRegion></affiliation></author><author><name sortKey="Shu, Haidong" sort="Shu, Haidong" uniqKey="Shu H" first="Haidong" last="Shu">Haidong Shu</name><affiliation wicri:level="1"><nlm:affiliation>Department of Plant Pathology, Nanjing Agricultural University, 210095 Nanjing, China.</nlm:affiliation><country xml:lang="fr">République populaire de Chine</country><wicri:regionArea>Department of Plant Pathology, Nanjing Agricultural University, 210095 Nanjing</wicri:regionArea><wicri:noRegion>210095 Nanjing</wicri:noRegion></affiliation><affiliation wicri:level="1"><nlm:affiliation>Key Laboratory of Integrated Management of Crop Diseases and Pests (Ministry of Education), College of Plant Protection, Nanjing Agricultural University, Nanjing 210095, China.</nlm:affiliation><country xml:lang="fr">République populaire de Chine</country><wicri:regionArea>Key Laboratory of Integrated Management of Crop Diseases and Pests (Ministry of Education), College of Plant Protection, Nanjing Agricultural University, Nanjing 210095</wicri:regionArea><wicri:noRegion>Nanjing 210095</wicri:noRegion></affiliation><affiliation wicri:level="1"><nlm:affiliation>The Key Laboratory of Plant Immunity, Nanjing Agricultural University, 210095 Nanjing, China.</nlm:affiliation><country xml:lang="fr">République populaire de Chine</country><wicri:regionArea>The Key Laboratory of Plant Immunity, Nanjing Agricultural University, 210095 Nanjing</wicri:regionArea><wicri:noRegion>210095 Nanjing</wicri:noRegion></affiliation></author><author><name sortKey="Xiao, Junhua" sort="Xiao, Junhua" uniqKey="Xiao J" first="Junhua" last="Xiao">Junhua Xiao</name><affiliation wicri:level="1"><nlm:affiliation>Department of Plant Pathology, Nanjing Agricultural University, 210095 Nanjing, China.</nlm:affiliation><country xml:lang="fr">République populaire de Chine</country><wicri:regionArea>Department of Plant Pathology, Nanjing Agricultural University, 210095 Nanjing</wicri:regionArea><wicri:noRegion>210095 Nanjing</wicri:noRegion></affiliation><affiliation wicri:level="1"><nlm:affiliation>Key Laboratory of Integrated Management of Crop Diseases and Pests (Ministry of Education), College of Plant Protection, Nanjing Agricultural University, Nanjing 210095, China.</nlm:affiliation><country xml:lang="fr">République populaire de Chine</country><wicri:regionArea>Key Laboratory of Integrated Management of Crop Diseases and Pests (Ministry of Education), College of Plant Protection, Nanjing Agricultural University, Nanjing 210095</wicri:regionArea><wicri:noRegion>Nanjing 210095</wicri:noRegion></affiliation><affiliation wicri:level="1"><nlm:affiliation>The Key Laboratory of Plant Immunity, Nanjing Agricultural University, 210095 Nanjing, China.</nlm:affiliation><country xml:lang="fr">République populaire de Chine</country><wicri:regionArea>The Key Laboratory of Plant Immunity, Nanjing Agricultural University, 210095 Nanjing</wicri:regionArea><wicri:noRegion>210095 Nanjing</wicri:noRegion></affiliation></author><author><name sortKey="Ye, Wenwu" sort="Ye, Wenwu" uniqKey="Ye W" first="Wenwu" last="Ye">Wenwu Ye</name><affiliation wicri:level="1"><nlm:affiliation>Department of Plant Pathology, Nanjing Agricultural University, 210095 Nanjing, China.</nlm:affiliation><country xml:lang="fr">République populaire de Chine</country><wicri:regionArea>Department of Plant Pathology, Nanjing Agricultural University, 210095 Nanjing</wicri:regionArea><wicri:noRegion>210095 Nanjing</wicri:noRegion></affiliation><affiliation wicri:level="1"><nlm:affiliation>Key Laboratory of Integrated Management of Crop Diseases and Pests (Ministry of Education), College of Plant Protection, Nanjing Agricultural University, Nanjing 210095, China.</nlm:affiliation><country xml:lang="fr">République populaire de Chine</country><wicri:regionArea>Key Laboratory of Integrated Management of Crop Diseases and Pests (Ministry of Education), College of Plant Protection, Nanjing Agricultural University, Nanjing 210095</wicri:regionArea><wicri:noRegion>Nanjing 210095</wicri:noRegion></affiliation><affiliation wicri:level="1"><nlm:affiliation>The Key Laboratory of Plant Immunity, Nanjing Agricultural University, 210095 Nanjing, China.</nlm:affiliation><country xml:lang="fr">République populaire de Chine</country><wicri:regionArea>The Key Laboratory of Plant Immunity, Nanjing Agricultural University, 210095 Nanjing</wicri:regionArea><wicri:noRegion>210095 Nanjing</wicri:noRegion></affiliation></author><author><name sortKey="Wang, Yan" sort="Wang, Yan" uniqKey="Wang Y" first="Yan" last="Wang">Yan Wang</name><affiliation wicri:level="1"><nlm:affiliation>Department of Plant Pathology, Nanjing Agricultural University, 210095 Nanjing, China.</nlm:affiliation><country xml:lang="fr">République populaire de Chine</country><wicri:regionArea>Department of Plant Pathology, Nanjing Agricultural University, 210095 Nanjing</wicri:regionArea><wicri:noRegion>210095 Nanjing</wicri:noRegion></affiliation><affiliation wicri:level="1"><nlm:affiliation>Key Laboratory of Integrated Management of Crop Diseases and Pests (Ministry of Education), College of Plant Protection, Nanjing Agricultural University, Nanjing 210095, China.</nlm:affiliation><country xml:lang="fr">République populaire de Chine</country><wicri:regionArea>Key Laboratory of Integrated Management of Crop Diseases and Pests (Ministry of Education), College of Plant Protection, Nanjing Agricultural University, Nanjing 210095</wicri:regionArea><wicri:noRegion>Nanjing 210095</wicri:noRegion></affiliation><affiliation wicri:level="1"><nlm:affiliation>The Key Laboratory of Plant Immunity, Nanjing Agricultural University, 210095 Nanjing, China.</nlm:affiliation><country xml:lang="fr">République populaire de Chine</country><wicri:regionArea>The Key Laboratory of Plant Immunity, Nanjing Agricultural University, 210095 Nanjing</wicri:regionArea><wicri:noRegion>210095 Nanjing</wicri:noRegion></affiliation></author><author><name sortKey="Wang, Yiming" sort="Wang, Yiming" uniqKey="Wang Y" first="Yiming" last="Wang">Yiming Wang</name><affiliation wicri:level="1"><nlm:affiliation>Department of Plant Pathology, Nanjing Agricultural University, 210095 Nanjing, China.</nlm:affiliation><country xml:lang="fr">République populaire de Chine</country><wicri:regionArea>Department of Plant Pathology, Nanjing Agricultural University, 210095 Nanjing</wicri:regionArea><wicri:noRegion>210095 Nanjing</wicri:noRegion></affiliation><affiliation wicri:level="1"><nlm:affiliation>Key Laboratory of Integrated Management of Crop Diseases and Pests (Ministry of Education), College of Plant Protection, Nanjing Agricultural University, Nanjing 210095, China.</nlm:affiliation><country xml:lang="fr">République populaire de Chine</country><wicri:regionArea>Key Laboratory of Integrated Management of Crop Diseases and Pests (Ministry of Education), College of Plant Protection, Nanjing Agricultural University, Nanjing 210095</wicri:regionArea><wicri:noRegion>Nanjing 210095</wicri:noRegion></affiliation><affiliation wicri:level="1"><nlm:affiliation>The Key Laboratory of Plant Immunity, Nanjing Agricultural University, 210095 Nanjing, China.</nlm:affiliation><country xml:lang="fr">République populaire de Chine</country><wicri:regionArea>The Key Laboratory of Plant Immunity, Nanjing Agricultural University, 210095 Nanjing</wicri:regionArea><wicri:noRegion>210095 Nanjing</wicri:noRegion></affiliation></author><author><name sortKey="Dong, Suomeng" sort="Dong, Suomeng" uniqKey="Dong S" first="Suomeng" last="Dong">Suomeng Dong</name><affiliation wicri:level="1"><nlm:affiliation>Department of Plant Pathology, Nanjing Agricultural University, 210095 Nanjing, China.</nlm:affiliation><country xml:lang="fr">République populaire de Chine</country><wicri:regionArea>Department of Plant Pathology, Nanjing Agricultural University, 210095 Nanjing</wicri:regionArea><wicri:noRegion>210095 Nanjing</wicri:noRegion></affiliation><affiliation wicri:level="1"><nlm:affiliation>Key Laboratory of Integrated Management of Crop Diseases and Pests (Ministry of Education), College of Plant Protection, Nanjing Agricultural University, Nanjing 210095, China.</nlm:affiliation><country xml:lang="fr">République populaire de Chine</country><wicri:regionArea>Key Laboratory of Integrated Management of Crop Diseases and Pests (Ministry of Education), College of Plant Protection, Nanjing Agricultural University, Nanjing 210095</wicri:regionArea><wicri:noRegion>Nanjing 210095</wicri:noRegion></affiliation><affiliation wicri:level="1"><nlm:affiliation>The Key Laboratory of Plant Immunity, Nanjing Agricultural University, 210095 Nanjing, China.</nlm:affiliation><country xml:lang="fr">République populaire de Chine</country><wicri:regionArea>The Key Laboratory of Plant Immunity, Nanjing Agricultural University, 210095 Nanjing</wicri:regionArea><wicri:noRegion>210095 Nanjing</wicri:noRegion></affiliation></author><author><name sortKey="Tyler, Brett M" sort="Tyler, Brett M" uniqKey="Tyler B" first="Brett M" last="Tyler">Brett M. Tyler</name><affiliation wicri:level="2"><nlm:affiliation>Center for Genome Research and Biocomputing, Oregon State University, Corvallis, OR 97331.</nlm:affiliation><country xml:lang="fr">États-Unis</country><placeName><region type="state">Oregon</region></placeName><wicri:cityArea>Center for Genome Research and Biocomputing, Oregon State University, Corvallis</wicri:cityArea></affiliation><affiliation wicri:level="2"><nlm:affiliation>Department of Botany and Plant Pathology, Oregon State University, Corvallis, OR 97331.</nlm:affiliation><country xml:lang="fr">États-Unis</country><placeName><region type="state">Oregon</region></placeName><wicri:cityArea>Department of Botany and Plant Pathology, Oregon State University, Corvallis</wicri:cityArea></affiliation></author><author><name sortKey="Wang, Yuanchao" sort="Wang, Yuanchao" uniqKey="Wang Y" first="Yuanchao" last="Wang">Yuanchao Wang</name><affiliation wicri:level="1"><nlm:affiliation>Department of Plant Pathology, Nanjing Agricultural University, 210095 Nanjing, China; wangyc@njau.edu.cn.</nlm:affiliation><country wicri:rule="url">République populaire de Chine</country><wicri:regionArea>Department of Plant Pathology, Nanjing Agricultural University, 210095 Nanjing</wicri:regionArea><wicri:noRegion>210095 Nanjing</wicri:noRegion></affiliation><affiliation wicri:level="1"><nlm:affiliation>Key Laboratory of Integrated Management of Crop Diseases and Pests (Ministry of Education), College of Plant Protection, Nanjing Agricultural University, Nanjing 210095, China.</nlm:affiliation><country xml:lang="fr">République populaire de Chine</country><wicri:regionArea>Key Laboratory of Integrated Management of Crop Diseases and Pests (Ministry of Education), College of Plant Protection, Nanjing Agricultural University, Nanjing 210095</wicri:regionArea><wicri:noRegion>Nanjing 210095</wicri:noRegion></affiliation><affiliation wicri:level="1"><nlm:affiliation>The Key Laboratory of Plant Immunity, Nanjing Agricultural University, 210095 Nanjing, China.</nlm:affiliation><country xml:lang="fr">République populaire de Chine</country><wicri:regionArea>The Key Laboratory of Plant Immunity, Nanjing Agricultural University, 210095 Nanjing</wicri:regionArea><wicri:noRegion>210095 Nanjing</wicri:noRegion></affiliation></author></titleStmt><publicationStmt><idno type="wicri:source">PubMed</idno><date when="2020">2020</date><idno type="RBID">pubmed:33082226</idno><idno type="pmid">33082226</idno><idno type="doi">10.1073/pnas.2012149117</idno><idno type="wicri:Area/Main/Corpus">000052</idno><idno type="wicri:explorRef" wicri:stream="Main" wicri:step="Corpus" wicri:corpus="PubMed">000052</idno><idno type="wicri:Area/Main/Curation">000052</idno><idno type="wicri:explorRef" wicri:stream="Main" wicri:step="Curation">000052</idno><idno type="wicri:Area/Main/Exploration">000052</idno></publicationStmt><sourceDesc><biblStruct><analytic><title xml:lang="en">N<i>-</i>glycosylation shields <i>Phytophthora sojae</i> apoplastic effector PsXEG1 from a specific host aspartic protease.</title><author><name sortKey="Xia, Yeqiang" sort="Xia, Yeqiang" uniqKey="Xia Y" first="Yeqiang" last="Xia">Yeqiang Xia</name><affiliation wicri:level="1"><nlm:affiliation>Department of Plant Pathology, Nanjing Agricultural University, 210095 Nanjing, China.</nlm:affiliation><country xml:lang="fr">République populaire de Chine</country><wicri:regionArea>Department of Plant Pathology, Nanjing Agricultural University, 210095 Nanjing</wicri:regionArea><wicri:noRegion>210095 Nanjing</wicri:noRegion></affiliation><affiliation wicri:level="1"><nlm:affiliation>Key Laboratory of Integrated Management of Crop Diseases and Pests (Ministry of Education), College of Plant Protection, Nanjing Agricultural University, Nanjing 210095, China.</nlm:affiliation><country xml:lang="fr">République populaire de Chine</country><wicri:regionArea>Key Laboratory of Integrated Management of Crop Diseases and Pests (Ministry of Education), College of Plant Protection, Nanjing Agricultural University, Nanjing 210095</wicri:regionArea><wicri:noRegion>Nanjing 210095</wicri:noRegion></affiliation><affiliation wicri:level="1"><nlm:affiliation>The Key Laboratory of Plant Immunity, Nanjing Agricultural University, 210095 Nanjing, China.</nlm:affiliation><country xml:lang="fr">République populaire de Chine</country><wicri:regionArea>The Key Laboratory of Plant Immunity, Nanjing Agricultural University, 210095 Nanjing</wicri:regionArea><wicri:noRegion>210095 Nanjing</wicri:noRegion></affiliation></author><author><name sortKey="Ma, Zhenchuan" sort="Ma, Zhenchuan" uniqKey="Ma Z" first="Zhenchuan" last="Ma">Zhenchuan Ma</name><affiliation wicri:level="1"><nlm:affiliation>Department of Plant Pathology, Nanjing Agricultural University, 210095 Nanjing, China.</nlm:affiliation><country xml:lang="fr">République populaire de Chine</country><wicri:regionArea>Department of Plant Pathology, Nanjing Agricultural University, 210095 Nanjing</wicri:regionArea><wicri:noRegion>210095 Nanjing</wicri:noRegion></affiliation><affiliation wicri:level="1"><nlm:affiliation>Key Laboratory of Integrated Management of Crop Diseases and Pests (Ministry of Education), College of Plant Protection, Nanjing Agricultural University, Nanjing 210095, China.</nlm:affiliation><country xml:lang="fr">République populaire de Chine</country><wicri:regionArea>Key Laboratory of Integrated Management of Crop Diseases and Pests (Ministry of Education), College of Plant Protection, Nanjing Agricultural University, Nanjing 210095</wicri:regionArea><wicri:noRegion>Nanjing 210095</wicri:noRegion></affiliation><affiliation wicri:level="1"><nlm:affiliation>The Key Laboratory of Plant Immunity, Nanjing Agricultural University, 210095 Nanjing, China.</nlm:affiliation><country xml:lang="fr">République populaire de Chine</country><wicri:regionArea>The Key Laboratory of Plant Immunity, Nanjing Agricultural University, 210095 Nanjing</wicri:regionArea><wicri:noRegion>210095 Nanjing</wicri:noRegion></affiliation></author><author><name sortKey="Qiu, Min" sort="Qiu, Min" uniqKey="Qiu M" first="Min" last="Qiu">Min Qiu</name><affiliation wicri:level="1"><nlm:affiliation>Department of Plant Pathology, Nanjing Agricultural University, 210095 Nanjing, China.</nlm:affiliation><country xml:lang="fr">République populaire de Chine</country><wicri:regionArea>Department of Plant Pathology, Nanjing Agricultural University, 210095 Nanjing</wicri:regionArea><wicri:noRegion>210095 Nanjing</wicri:noRegion></affiliation><affiliation wicri:level="1"><nlm:affiliation>Key Laboratory of Integrated Management of Crop Diseases and Pests (Ministry of Education), College of Plant Protection, Nanjing Agricultural University, Nanjing 210095, China.</nlm:affiliation><country xml:lang="fr">République populaire de Chine</country><wicri:regionArea>Key Laboratory of Integrated Management of Crop Diseases and Pests (Ministry of Education), College of Plant Protection, Nanjing Agricultural University, Nanjing 210095</wicri:regionArea><wicri:noRegion>Nanjing 210095</wicri:noRegion></affiliation><affiliation wicri:level="1"><nlm:affiliation>The Key Laboratory of Plant Immunity, Nanjing Agricultural University, 210095 Nanjing, China.</nlm:affiliation><country xml:lang="fr">République populaire de Chine</country><wicri:regionArea>The Key Laboratory of Plant Immunity, Nanjing Agricultural University, 210095 Nanjing</wicri:regionArea><wicri:noRegion>210095 Nanjing</wicri:noRegion></affiliation></author><author><name sortKey="Guo, Baodian" sort="Guo, Baodian" uniqKey="Guo B" first="Baodian" last="Guo">Baodian Guo</name><affiliation wicri:level="1"><nlm:affiliation>Department of Plant Pathology, Nanjing Agricultural University, 210095 Nanjing, China.</nlm:affiliation><country xml:lang="fr">République populaire de Chine</country><wicri:regionArea>Department of Plant Pathology, Nanjing Agricultural University, 210095 Nanjing</wicri:regionArea><wicri:noRegion>210095 Nanjing</wicri:noRegion></affiliation><affiliation wicri:level="1"><nlm:affiliation>Key Laboratory of Integrated Management of Crop Diseases and Pests (Ministry of Education), College of Plant Protection, Nanjing Agricultural University, Nanjing 210095, China.</nlm:affiliation><country xml:lang="fr">République populaire de Chine</country><wicri:regionArea>Key Laboratory of Integrated Management of Crop Diseases and Pests (Ministry of Education), College of Plant Protection, Nanjing Agricultural University, Nanjing 210095</wicri:regionArea><wicri:noRegion>Nanjing 210095</wicri:noRegion></affiliation><affiliation wicri:level="1"><nlm:affiliation>The Key Laboratory of Plant Immunity, Nanjing Agricultural University, 210095 Nanjing, China.</nlm:affiliation><country xml:lang="fr">République populaire de Chine</country><wicri:regionArea>The Key Laboratory of Plant Immunity, Nanjing Agricultural University, 210095 Nanjing</wicri:regionArea><wicri:noRegion>210095 Nanjing</wicri:noRegion></affiliation></author><author><name sortKey="Zhang, Qi" sort="Zhang, Qi" uniqKey="Zhang Q" first="Qi" last="Zhang">Qi Zhang</name><affiliation wicri:level="1"><nlm:affiliation>Department of Plant Pathology, Nanjing Agricultural University, 210095 Nanjing, China.</nlm:affiliation><country xml:lang="fr">République populaire de Chine</country><wicri:regionArea>Department of Plant Pathology, Nanjing Agricultural University, 210095 Nanjing</wicri:regionArea><wicri:noRegion>210095 Nanjing</wicri:noRegion></affiliation><affiliation wicri:level="1"><nlm:affiliation>Key Laboratory of Integrated Management of Crop Diseases and Pests (Ministry of Education), College of Plant Protection, Nanjing Agricultural University, Nanjing 210095, China.</nlm:affiliation><country xml:lang="fr">République populaire de Chine</country><wicri:regionArea>Key Laboratory of Integrated Management of Crop Diseases and Pests (Ministry of Education), College of Plant Protection, Nanjing Agricultural University, Nanjing 210095</wicri:regionArea><wicri:noRegion>Nanjing 210095</wicri:noRegion></affiliation><affiliation wicri:level="1"><nlm:affiliation>The Key Laboratory of Plant Immunity, Nanjing Agricultural University, 210095 Nanjing, China.</nlm:affiliation><country xml:lang="fr">République populaire de Chine</country><wicri:regionArea>The Key Laboratory of Plant Immunity, Nanjing Agricultural University, 210095 Nanjing</wicri:regionArea><wicri:noRegion>210095 Nanjing</wicri:noRegion></affiliation></author><author><name sortKey="Jiang, Haibin" sort="Jiang, Haibin" uniqKey="Jiang H" first="Haibin" last="Jiang">Haibin Jiang</name><affiliation wicri:level="1"><nlm:affiliation>Department of Plant Pathology, Nanjing Agricultural University, 210095 Nanjing, China.</nlm:affiliation><country xml:lang="fr">République populaire de Chine</country><wicri:regionArea>Department of Plant Pathology, Nanjing Agricultural University, 210095 Nanjing</wicri:regionArea><wicri:noRegion>210095 Nanjing</wicri:noRegion></affiliation><affiliation wicri:level="1"><nlm:affiliation>Key Laboratory of Integrated Management of Crop Diseases and Pests (Ministry of Education), College of Plant Protection, Nanjing Agricultural University, Nanjing 210095, China.</nlm:affiliation><country xml:lang="fr">République populaire de Chine</country><wicri:regionArea>Key Laboratory of Integrated Management of Crop Diseases and Pests (Ministry of Education), College of Plant Protection, Nanjing Agricultural University, Nanjing 210095</wicri:regionArea><wicri:noRegion>Nanjing 210095</wicri:noRegion></affiliation><affiliation wicri:level="1"><nlm:affiliation>The Key Laboratory of Plant Immunity, Nanjing Agricultural University, 210095 Nanjing, China.</nlm:affiliation><country xml:lang="fr">République populaire de Chine</country><wicri:regionArea>The Key Laboratory of Plant Immunity, Nanjing Agricultural University, 210095 Nanjing</wicri:regionArea><wicri:noRegion>210095 Nanjing</wicri:noRegion></affiliation></author><author><name sortKey="Zhang, Baiyu" sort="Zhang, Baiyu" uniqKey="Zhang B" first="Baiyu" last="Zhang">Baiyu Zhang</name><affiliation wicri:level="1"><nlm:affiliation>Department of Plant Pathology, Nanjing Agricultural University, 210095 Nanjing, China.</nlm:affiliation><country xml:lang="fr">République populaire de Chine</country><wicri:regionArea>Department of Plant Pathology, Nanjing Agricultural University, 210095 Nanjing</wicri:regionArea><wicri:noRegion>210095 Nanjing</wicri:noRegion></affiliation><affiliation wicri:level="1"><nlm:affiliation>Key Laboratory of Integrated Management of Crop Diseases and Pests (Ministry of Education), College of Plant Protection, Nanjing Agricultural University, Nanjing 210095, China.</nlm:affiliation><country xml:lang="fr">République populaire de Chine</country><wicri:regionArea>Key Laboratory of Integrated Management of Crop Diseases and Pests (Ministry of Education), College of Plant Protection, Nanjing Agricultural University, Nanjing 210095</wicri:regionArea><wicri:noRegion>Nanjing 210095</wicri:noRegion></affiliation><affiliation wicri:level="1"><nlm:affiliation>The Key Laboratory of Plant Immunity, Nanjing Agricultural University, 210095 Nanjing, China.</nlm:affiliation><country xml:lang="fr">République populaire de Chine</country><wicri:regionArea>The Key Laboratory of Plant Immunity, Nanjing Agricultural University, 210095 Nanjing</wicri:regionArea><wicri:noRegion>210095 Nanjing</wicri:noRegion></affiliation></author><author><name sortKey="Lin, Yachun" sort="Lin, Yachun" uniqKey="Lin Y" first="Yachun" last="Lin">Yachun Lin</name><affiliation wicri:level="1"><nlm:affiliation>Department of Plant Pathology, Nanjing Agricultural University, 210095 Nanjing, China.</nlm:affiliation><country xml:lang="fr">République populaire de Chine</country><wicri:regionArea>Department of Plant Pathology, Nanjing Agricultural University, 210095 Nanjing</wicri:regionArea><wicri:noRegion>210095 Nanjing</wicri:noRegion></affiliation><affiliation wicri:level="1"><nlm:affiliation>Key Laboratory of Integrated Management of Crop Diseases and Pests (Ministry of Education), College of Plant Protection, Nanjing Agricultural University, Nanjing 210095, China.</nlm:affiliation><country xml:lang="fr">République populaire de Chine</country><wicri:regionArea>Key Laboratory of Integrated Management of Crop Diseases and Pests (Ministry of Education), College of Plant Protection, Nanjing Agricultural University, Nanjing 210095</wicri:regionArea><wicri:noRegion>Nanjing 210095</wicri:noRegion></affiliation><affiliation wicri:level="1"><nlm:affiliation>The Key Laboratory of Plant Immunity, Nanjing Agricultural University, 210095 Nanjing, China.</nlm:affiliation><country xml:lang="fr">République populaire de Chine</country><wicri:regionArea>The Key Laboratory of Plant Immunity, Nanjing Agricultural University, 210095 Nanjing</wicri:regionArea><wicri:noRegion>210095 Nanjing</wicri:noRegion></affiliation></author><author><name sortKey="Xuan, Mingrun" sort="Xuan, Mingrun" uniqKey="Xuan M" first="Mingrun" last="Xuan">Mingrun Xuan</name><affiliation wicri:level="1"><nlm:affiliation>Department of Plant Pathology, Nanjing Agricultural University, 210095 Nanjing, China.</nlm:affiliation><country xml:lang="fr">République populaire de Chine</country><wicri:regionArea>Department of Plant Pathology, Nanjing Agricultural University, 210095 Nanjing</wicri:regionArea><wicri:noRegion>210095 Nanjing</wicri:noRegion></affiliation><affiliation wicri:level="1"><nlm:affiliation>Key Laboratory of Integrated Management of Crop Diseases and Pests (Ministry of Education), College of Plant Protection, Nanjing Agricultural University, Nanjing 210095, China.</nlm:affiliation><country xml:lang="fr">République populaire de Chine</country><wicri:regionArea>Key Laboratory of Integrated Management of Crop Diseases and Pests (Ministry of Education), College of Plant Protection, Nanjing Agricultural University, Nanjing 210095</wicri:regionArea><wicri:noRegion>Nanjing 210095</wicri:noRegion></affiliation><affiliation wicri:level="1"><nlm:affiliation>The Key Laboratory of Plant Immunity, Nanjing Agricultural University, 210095 Nanjing, China.</nlm:affiliation><country xml:lang="fr">République populaire de Chine</country><wicri:regionArea>The Key Laboratory of Plant Immunity, Nanjing Agricultural University, 210095 Nanjing</wicri:regionArea><wicri:noRegion>210095 Nanjing</wicri:noRegion></affiliation></author><author><name sortKey="Sun, Liang" sort="Sun, Liang" uniqKey="Sun L" first="Liang" last="Sun">Liang Sun</name><affiliation wicri:level="1"><nlm:affiliation>Department of Plant Pathology, Nanjing Agricultural University, 210095 Nanjing, China.</nlm:affiliation><country xml:lang="fr">République populaire de Chine</country><wicri:regionArea>Department of Plant Pathology, Nanjing Agricultural University, 210095 Nanjing</wicri:regionArea><wicri:noRegion>210095 Nanjing</wicri:noRegion></affiliation><affiliation wicri:level="1"><nlm:affiliation>Key Laboratory of Integrated Management of Crop Diseases and Pests (Ministry of Education), College of Plant Protection, Nanjing Agricultural University, Nanjing 210095, China.</nlm:affiliation><country xml:lang="fr">République populaire de Chine</country><wicri:regionArea>Key Laboratory of Integrated Management of Crop Diseases and Pests (Ministry of Education), College of Plant Protection, Nanjing Agricultural University, Nanjing 210095</wicri:regionArea><wicri:noRegion>Nanjing 210095</wicri:noRegion></affiliation><affiliation wicri:level="1"><nlm:affiliation>The Key Laboratory of Plant Immunity, Nanjing Agricultural University, 210095 Nanjing, China.</nlm:affiliation><country xml:lang="fr">République populaire de Chine</country><wicri:regionArea>The Key Laboratory of Plant Immunity, Nanjing Agricultural University, 210095 Nanjing</wicri:regionArea><wicri:noRegion>210095 Nanjing</wicri:noRegion></affiliation></author><author><name sortKey="Shu, Haidong" sort="Shu, Haidong" uniqKey="Shu H" first="Haidong" last="Shu">Haidong Shu</name><affiliation wicri:level="1"><nlm:affiliation>Department of Plant Pathology, Nanjing Agricultural University, 210095 Nanjing, China.</nlm:affiliation><country xml:lang="fr">République populaire de Chine</country><wicri:regionArea>Department of Plant Pathology, Nanjing Agricultural University, 210095 Nanjing</wicri:regionArea><wicri:noRegion>210095 Nanjing</wicri:noRegion></affiliation><affiliation wicri:level="1"><nlm:affiliation>Key Laboratory of Integrated Management of Crop Diseases and Pests (Ministry of Education), College of Plant Protection, Nanjing Agricultural University, Nanjing 210095, China.</nlm:affiliation><country xml:lang="fr">République populaire de Chine</country><wicri:regionArea>Key Laboratory of Integrated Management of Crop Diseases and Pests (Ministry of Education), College of Plant Protection, Nanjing Agricultural University, Nanjing 210095</wicri:regionArea><wicri:noRegion>Nanjing 210095</wicri:noRegion></affiliation><affiliation wicri:level="1"><nlm:affiliation>The Key Laboratory of Plant Immunity, Nanjing Agricultural University, 210095 Nanjing, China.</nlm:affiliation><country xml:lang="fr">République populaire de Chine</country><wicri:regionArea>The Key Laboratory of Plant Immunity, Nanjing Agricultural University, 210095 Nanjing</wicri:regionArea><wicri:noRegion>210095 Nanjing</wicri:noRegion></affiliation></author><author><name sortKey="Xiao, Junhua" sort="Xiao, Junhua" uniqKey="Xiao J" first="Junhua" last="Xiao">Junhua Xiao</name><affiliation wicri:level="1"><nlm:affiliation>Department of Plant Pathology, Nanjing Agricultural University, 210095 Nanjing, China.</nlm:affiliation><country xml:lang="fr">République populaire de Chine</country><wicri:regionArea>Department of Plant Pathology, Nanjing Agricultural University, 210095 Nanjing</wicri:regionArea><wicri:noRegion>210095 Nanjing</wicri:noRegion></affiliation><affiliation wicri:level="1"><nlm:affiliation>Key Laboratory of Integrated Management of Crop Diseases and Pests (Ministry of Education), College of Plant Protection, Nanjing Agricultural University, Nanjing 210095, China.</nlm:affiliation><country xml:lang="fr">République populaire de Chine</country><wicri:regionArea>Key Laboratory of Integrated Management of Crop Diseases and Pests (Ministry of Education), College of Plant Protection, Nanjing Agricultural University, Nanjing 210095</wicri:regionArea><wicri:noRegion>Nanjing 210095</wicri:noRegion></affiliation><affiliation wicri:level="1"><nlm:affiliation>The Key Laboratory of Plant Immunity, Nanjing Agricultural University, 210095 Nanjing, China.</nlm:affiliation><country xml:lang="fr">République populaire de Chine</country><wicri:regionArea>The Key Laboratory of Plant Immunity, Nanjing Agricultural University, 210095 Nanjing</wicri:regionArea><wicri:noRegion>210095 Nanjing</wicri:noRegion></affiliation></author><author><name sortKey="Ye, Wenwu" sort="Ye, Wenwu" uniqKey="Ye W" first="Wenwu" last="Ye">Wenwu Ye</name><affiliation wicri:level="1"><nlm:affiliation>Department of Plant Pathology, Nanjing Agricultural University, 210095 Nanjing, China.</nlm:affiliation><country xml:lang="fr">République populaire de Chine</country><wicri:regionArea>Department of Plant Pathology, Nanjing Agricultural University, 210095 Nanjing</wicri:regionArea><wicri:noRegion>210095 Nanjing</wicri:noRegion></affiliation><affiliation wicri:level="1"><nlm:affiliation>Key Laboratory of Integrated Management of Crop Diseases and Pests (Ministry of Education), College of Plant Protection, Nanjing Agricultural University, Nanjing 210095, China.</nlm:affiliation><country xml:lang="fr">République populaire de Chine</country><wicri:regionArea>Key Laboratory of Integrated Management of Crop Diseases and Pests (Ministry of Education), College of Plant Protection, Nanjing Agricultural University, Nanjing 210095</wicri:regionArea><wicri:noRegion>Nanjing 210095</wicri:noRegion></affiliation><affiliation wicri:level="1"><nlm:affiliation>The Key Laboratory of Plant Immunity, Nanjing Agricultural University, 210095 Nanjing, China.</nlm:affiliation><country xml:lang="fr">République populaire de Chine</country><wicri:regionArea>The Key Laboratory of Plant Immunity, Nanjing Agricultural University, 210095 Nanjing</wicri:regionArea><wicri:noRegion>210095 Nanjing</wicri:noRegion></affiliation></author><author><name sortKey="Wang, Yan" sort="Wang, Yan" uniqKey="Wang Y" first="Yan" last="Wang">Yan Wang</name><affiliation wicri:level="1"><nlm:affiliation>Department of Plant Pathology, Nanjing Agricultural University, 210095 Nanjing, China.</nlm:affiliation><country xml:lang="fr">République populaire de Chine</country><wicri:regionArea>Department of Plant Pathology, Nanjing Agricultural University, 210095 Nanjing</wicri:regionArea><wicri:noRegion>210095 Nanjing</wicri:noRegion></affiliation><affiliation wicri:level="1"><nlm:affiliation>Key Laboratory of Integrated Management of Crop Diseases and Pests (Ministry of Education), College of Plant Protection, Nanjing Agricultural University, Nanjing 210095, China.</nlm:affiliation><country xml:lang="fr">République populaire de Chine</country><wicri:regionArea>Key Laboratory of Integrated Management of Crop Diseases and Pests (Ministry of Education), College of Plant Protection, Nanjing Agricultural University, Nanjing 210095</wicri:regionArea><wicri:noRegion>Nanjing 210095</wicri:noRegion></affiliation><affiliation wicri:level="1"><nlm:affiliation>The Key Laboratory of Plant Immunity, Nanjing Agricultural University, 210095 Nanjing, China.</nlm:affiliation><country xml:lang="fr">République populaire de Chine</country><wicri:regionArea>The Key Laboratory of Plant Immunity, Nanjing Agricultural University, 210095 Nanjing</wicri:regionArea><wicri:noRegion>210095 Nanjing</wicri:noRegion></affiliation></author><author><name sortKey="Wang, Yiming" sort="Wang, Yiming" uniqKey="Wang Y" first="Yiming" last="Wang">Yiming Wang</name><affiliation wicri:level="1"><nlm:affiliation>Department of Plant Pathology, Nanjing Agricultural University, 210095 Nanjing, China.</nlm:affiliation><country xml:lang="fr">République populaire de Chine</country><wicri:regionArea>Department of Plant Pathology, Nanjing Agricultural University, 210095 Nanjing</wicri:regionArea><wicri:noRegion>210095 Nanjing</wicri:noRegion></affiliation><affiliation wicri:level="1"><nlm:affiliation>Key Laboratory of Integrated Management of Crop Diseases and Pests (Ministry of Education), College of Plant Protection, Nanjing Agricultural University, Nanjing 210095, China.</nlm:affiliation><country xml:lang="fr">République populaire de Chine</country><wicri:regionArea>Key Laboratory of Integrated Management of Crop Diseases and Pests (Ministry of Education), College of Plant Protection, Nanjing Agricultural University, Nanjing 210095</wicri:regionArea><wicri:noRegion>Nanjing 210095</wicri:noRegion></affiliation><affiliation wicri:level="1"><nlm:affiliation>The Key Laboratory of Plant Immunity, Nanjing Agricultural University, 210095 Nanjing, China.</nlm:affiliation><country xml:lang="fr">République populaire de Chine</country><wicri:regionArea>The Key Laboratory of Plant Immunity, Nanjing Agricultural University, 210095 Nanjing</wicri:regionArea><wicri:noRegion>210095 Nanjing</wicri:noRegion></affiliation></author><author><name sortKey="Dong, Suomeng" sort="Dong, Suomeng" uniqKey="Dong S" first="Suomeng" last="Dong">Suomeng Dong</name><affiliation wicri:level="1"><nlm:affiliation>Department of Plant Pathology, Nanjing Agricultural University, 210095 Nanjing, China.</nlm:affiliation><country xml:lang="fr">République populaire de Chine</country><wicri:regionArea>Department of Plant Pathology, Nanjing Agricultural University, 210095 Nanjing</wicri:regionArea><wicri:noRegion>210095 Nanjing</wicri:noRegion></affiliation><affiliation wicri:level="1"><nlm:affiliation>Key Laboratory of Integrated Management of Crop Diseases and Pests (Ministry of Education), College of Plant Protection, Nanjing Agricultural University, Nanjing 210095, China.</nlm:affiliation><country xml:lang="fr">République populaire de Chine</country><wicri:regionArea>Key Laboratory of Integrated Management of Crop Diseases and Pests (Ministry of Education), College of Plant Protection, Nanjing Agricultural University, Nanjing 210095</wicri:regionArea><wicri:noRegion>Nanjing 210095</wicri:noRegion></affiliation><affiliation wicri:level="1"><nlm:affiliation>The Key Laboratory of Plant Immunity, Nanjing Agricultural University, 210095 Nanjing, China.</nlm:affiliation><country xml:lang="fr">République populaire de Chine</country><wicri:regionArea>The Key Laboratory of Plant Immunity, Nanjing Agricultural University, 210095 Nanjing</wicri:regionArea><wicri:noRegion>210095 Nanjing</wicri:noRegion></affiliation></author><author><name sortKey="Tyler, Brett M" sort="Tyler, Brett M" uniqKey="Tyler B" first="Brett M" last="Tyler">Brett M. Tyler</name><affiliation wicri:level="2"><nlm:affiliation>Center for Genome Research and Biocomputing, Oregon State University, Corvallis, OR 97331.</nlm:affiliation><country xml:lang="fr">États-Unis</country><placeName><region type="state">Oregon</region></placeName><wicri:cityArea>Center for Genome Research and Biocomputing, Oregon State University, Corvallis</wicri:cityArea></affiliation><affiliation wicri:level="2"><nlm:affiliation>Department of Botany and Plant Pathology, Oregon State University, Corvallis, OR 97331.</nlm:affiliation><country xml:lang="fr">États-Unis</country><placeName><region type="state">Oregon</region></placeName><wicri:cityArea>Department of Botany and Plant Pathology, Oregon State University, Corvallis</wicri:cityArea></affiliation></author><author><name sortKey="Wang, Yuanchao" sort="Wang, Yuanchao" uniqKey="Wang Y" first="Yuanchao" last="Wang">Yuanchao Wang</name><affiliation wicri:level="1"><nlm:affiliation>Department of Plant Pathology, Nanjing Agricultural University, 210095 Nanjing, China; wangyc@njau.edu.cn.</nlm:affiliation><country wicri:rule="url">République populaire de Chine</country><wicri:regionArea>Department of Plant Pathology, Nanjing Agricultural University, 210095 Nanjing</wicri:regionArea><wicri:noRegion>210095 Nanjing</wicri:noRegion></affiliation><affiliation wicri:level="1"><nlm:affiliation>Key Laboratory of Integrated Management of Crop Diseases and Pests (Ministry of Education), College of Plant Protection, Nanjing Agricultural University, Nanjing 210095, China.</nlm:affiliation><country xml:lang="fr">République populaire de Chine</country><wicri:regionArea>Key Laboratory of Integrated Management of Crop Diseases and Pests (Ministry of Education), College of Plant Protection, Nanjing Agricultural University, Nanjing 210095</wicri:regionArea><wicri:noRegion>Nanjing 210095</wicri:noRegion></affiliation><affiliation wicri:level="1"><nlm:affiliation>The Key Laboratory of Plant Immunity, Nanjing Agricultural University, 210095 Nanjing, China.</nlm:affiliation><country xml:lang="fr">République populaire de Chine</country><wicri:regionArea>The Key Laboratory of Plant Immunity, Nanjing Agricultural University, 210095 Nanjing</wicri:regionArea><wicri:noRegion>210095 Nanjing</wicri:noRegion></affiliation></author></analytic><series><title level="j">Proceedings of the National Academy of Sciences of the United States of America</title><idno type="eISSN">1091-6490</idno><imprint><date when="2020" type="published">2020</date></imprint></series></biblStruct></sourceDesc></fileDesc><profileDesc><textClass></textClass></profileDesc></teiHeader><front><div type="abstract" xml:lang="en">Hosts and pathogens are engaged in a continuous evolutionary struggle for physiological dominance. A major site of this struggle is the apoplast. In <i>Phytophthora sojae</i>-soybean interactions, PsXEG1, a pathogen-secreted apoplastic endoglucanase, is a key focal point of this struggle, and the subject of two layers of host defense and pathogen counterdefense. Here, we show that N-glycosylation of PsXEG1 represents an additional layer of this coevolutionary struggle, protecting PsXEG1 against a host apoplastic aspartic protease, GmAP5, that specifically targets PsXEG1. This posttranslational modification also attenuated binding by the previously described host inhibitor, GmGIP1. N-glycosylation of PsXEG1 at N174 and N190 inhibited binding and degradation by GmAP5 and was essential for <i>PsXEG1</i>'s full virulence contribution, except in GmAP5-silenced soybeans. Silencing of GmAP5 reduced soybean resistance against WT <i>P. sojae</i> but not against <i>PsXEG1</i> deletion strains of <i>P. sojae.</i> The crucial role of N-glycosylation within the three layers of defense and counterdefense centered on PsXEG1 highlight the critical importance of this conserved apoplastic effector and its posttranslational modification in <i>Phytophthora</i>-host coevolutionary conflict.</div></front></TEI><pubmed><MedlineCitation Status="In-Data-Review" Owner="NLM"><PMID Version="1">33082226</PMID><DateRevised><Year>2020</Year><Month>11</Month><Day>04</Day></DateRevised><Article PubModel="Print-Electronic"><Journal><ISSN IssnType="Electronic">1091-6490</ISSN><JournalIssue CitedMedium="Internet"><Volume>117</Volume><Issue>44</Issue><PubDate><Year>2020</Year><Month>Nov</Month><Day>03</Day></PubDate></JournalIssue><Title>Proceedings of the National Academy of Sciences of the United States of America</Title><ISOAbbreviation>Proc Natl Acad Sci U S A</ISOAbbreviation></Journal><ArticleTitle>N<i>-</i>glycosylation shields <i>Phytophthora sojae</i> apoplastic effector PsXEG1 from a specific host aspartic protease.</ArticleTitle><Pagination><MedlinePgn>27685-27693</MedlinePgn></Pagination><ELocationID EIdType="doi" ValidYN="Y">10.1073/pnas.2012149117</ELocationID><Abstract><AbstractText>Hosts and pathogens are engaged in a continuous evolutionary struggle for physiological dominance. A major site of this struggle is the apoplast. In <i>Phytophthora sojae</i>-soybean interactions, PsXEG1, a pathogen-secreted apoplastic endoglucanase, is a key focal point of this struggle, and the subject of two layers of host defense and pathogen counterdefense. Here, we show that N-glycosylation of PsXEG1 represents an additional layer of this coevolutionary struggle, protecting PsXEG1 against a host apoplastic aspartic protease, GmAP5, that specifically targets PsXEG1. This posttranslational modification also attenuated binding by the previously described host inhibitor, GmGIP1. N-glycosylation of PsXEG1 at N174 and N190 inhibited binding and degradation by GmAP5 and was essential for <i>PsXEG1</i>'s full virulence contribution, except in GmAP5-silenced soybeans. Silencing of GmAP5 reduced soybean resistance against WT <i>P. sojae</i> but not against <i>PsXEG1</i> deletion strains of <i>P. sojae.</i> The crucial role of N-glycosylation within the three layers of defense and counterdefense centered on PsXEG1 highlight the critical importance of this conserved apoplastic effector and its posttranslational modification in <i>Phytophthora</i>-host coevolutionary conflict.</AbstractText><CopyrightInformation>Copyright © 2020 the Author(s). Published by PNAS.</CopyrightInformation></Abstract><AuthorList CompleteYN="Y"><Author ValidYN="Y"><LastName>Xia</LastName><ForeName>Yeqiang</ForeName><Initials>Y</Initials><AffiliationInfo><Affiliation>Department of Plant Pathology, Nanjing Agricultural University, 210095 Nanjing, China.</Affiliation></AffiliationInfo><AffiliationInfo><Affiliation>Key Laboratory of Integrated Management of Crop Diseases and Pests (Ministry of Education), College of Plant Protection, Nanjing Agricultural University, Nanjing 210095, China.</Affiliation></AffiliationInfo><AffiliationInfo><Affiliation>The Key Laboratory of Plant Immunity, Nanjing Agricultural University, 210095 Nanjing, China.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Ma</LastName><ForeName>Zhenchuan</ForeName><Initials>Z</Initials><Identifier Source="ORCID">https://orcid.org/0000-0002-8478-2833</Identifier><AffiliationInfo><Affiliation>Department of Plant Pathology, Nanjing Agricultural University, 210095 Nanjing, China.</Affiliation></AffiliationInfo><AffiliationInfo><Affiliation>Key Laboratory of Integrated Management of Crop Diseases and Pests (Ministry of Education), College of Plant Protection, Nanjing Agricultural University, Nanjing 210095, China.</Affiliation></AffiliationInfo><AffiliationInfo><Affiliation>The Key Laboratory of Plant Immunity, Nanjing Agricultural University, 210095 Nanjing, China.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Qiu</LastName><ForeName>Min</ForeName><Initials>M</Initials><AffiliationInfo><Affiliation>Department of Plant Pathology, Nanjing Agricultural University, 210095 Nanjing, China.</Affiliation></AffiliationInfo><AffiliationInfo><Affiliation>Key Laboratory of Integrated Management of Crop Diseases and Pests (Ministry of Education), College of Plant Protection, Nanjing Agricultural University, Nanjing 210095, China.</Affiliation></AffiliationInfo><AffiliationInfo><Affiliation>The Key Laboratory of Plant Immunity, Nanjing Agricultural University, 210095 Nanjing, China.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Guo</LastName><ForeName>Baodian</ForeName><Initials>B</Initials><AffiliationInfo><Affiliation>Department of Plant Pathology, Nanjing Agricultural University, 210095 Nanjing, China.</Affiliation></AffiliationInfo><AffiliationInfo><Affiliation>Key Laboratory of Integrated Management of Crop Diseases and Pests (Ministry of Education), College of Plant Protection, Nanjing Agricultural University, Nanjing 210095, China.</Affiliation></AffiliationInfo><AffiliationInfo><Affiliation>The Key Laboratory of Plant Immunity, Nanjing Agricultural University, 210095 Nanjing, China.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Zhang</LastName><ForeName>Qi</ForeName><Initials>Q</Initials><AffiliationInfo><Affiliation>Department of Plant Pathology, Nanjing Agricultural University, 210095 Nanjing, China.</Affiliation></AffiliationInfo><AffiliationInfo><Affiliation>Key Laboratory of Integrated Management of Crop Diseases and Pests (Ministry of Education), College of Plant Protection, Nanjing Agricultural University, Nanjing 210095, China.</Affiliation></AffiliationInfo><AffiliationInfo><Affiliation>The Key Laboratory of Plant Immunity, Nanjing Agricultural University, 210095 Nanjing, China.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Jiang</LastName><ForeName>Haibin</ForeName><Initials>H</Initials><AffiliationInfo><Affiliation>Department of Plant Pathology, Nanjing Agricultural University, 210095 Nanjing, China.</Affiliation></AffiliationInfo><AffiliationInfo><Affiliation>Key Laboratory of Integrated Management of Crop Diseases and Pests (Ministry of Education), College of Plant Protection, Nanjing Agricultural University, Nanjing 210095, China.</Affiliation></AffiliationInfo><AffiliationInfo><Affiliation>The Key Laboratory of Plant Immunity, Nanjing Agricultural University, 210095 Nanjing, China.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Zhang</LastName><ForeName>Baiyu</ForeName><Initials>B</Initials><AffiliationInfo><Affiliation>Department of Plant Pathology, Nanjing Agricultural University, 210095 Nanjing, China.</Affiliation></AffiliationInfo><AffiliationInfo><Affiliation>Key Laboratory of Integrated Management of Crop Diseases and Pests (Ministry of Education), College of Plant Protection, Nanjing Agricultural University, Nanjing 210095, China.</Affiliation></AffiliationInfo><AffiliationInfo><Affiliation>The Key Laboratory of Plant Immunity, Nanjing Agricultural University, 210095 Nanjing, China.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Lin</LastName><ForeName>Yachun</ForeName><Initials>Y</Initials><Identifier Source="ORCID">https://orcid.org/0000-0001-7353-8918</Identifier><AffiliationInfo><Affiliation>Department of Plant Pathology, Nanjing Agricultural University, 210095 Nanjing, China.</Affiliation></AffiliationInfo><AffiliationInfo><Affiliation>Key Laboratory of Integrated Management of Crop Diseases and Pests (Ministry of Education), College of Plant Protection, Nanjing Agricultural University, Nanjing 210095, China.</Affiliation></AffiliationInfo><AffiliationInfo><Affiliation>The Key Laboratory of Plant Immunity, Nanjing Agricultural University, 210095 Nanjing, China.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Xuan</LastName><ForeName>Mingrun</ForeName><Initials>M</Initials><AffiliationInfo><Affiliation>Department of Plant Pathology, Nanjing Agricultural University, 210095 Nanjing, China.</Affiliation></AffiliationInfo><AffiliationInfo><Affiliation>Key Laboratory of Integrated Management of Crop Diseases and Pests (Ministry of Education), College of Plant Protection, Nanjing Agricultural University, Nanjing 210095, China.</Affiliation></AffiliationInfo><AffiliationInfo><Affiliation>The Key Laboratory of Plant Immunity, Nanjing Agricultural University, 210095 Nanjing, China.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Sun</LastName><ForeName>Liang</ForeName><Initials>L</Initials><AffiliationInfo><Affiliation>Department of Plant Pathology, Nanjing Agricultural University, 210095 Nanjing, China.</Affiliation></AffiliationInfo><AffiliationInfo><Affiliation>Key Laboratory of Integrated Management of Crop Diseases and Pests (Ministry of Education), College of Plant Protection, Nanjing Agricultural University, Nanjing 210095, China.</Affiliation></AffiliationInfo><AffiliationInfo><Affiliation>The Key Laboratory of Plant Immunity, Nanjing Agricultural University, 210095 Nanjing, China.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Shu</LastName><ForeName>Haidong</ForeName><Initials>H</Initials><AffiliationInfo><Affiliation>Department of Plant Pathology, Nanjing Agricultural University, 210095 Nanjing, China.</Affiliation></AffiliationInfo><AffiliationInfo><Affiliation>Key Laboratory of Integrated Management of Crop Diseases and Pests (Ministry of Education), College of Plant Protection, Nanjing Agricultural University, Nanjing 210095, China.</Affiliation></AffiliationInfo><AffiliationInfo><Affiliation>The Key Laboratory of Plant Immunity, Nanjing Agricultural University, 210095 Nanjing, China.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Xiao</LastName><ForeName>Junhua</ForeName><Initials>J</Initials><AffiliationInfo><Affiliation>Department of Plant Pathology, Nanjing Agricultural University, 210095 Nanjing, China.</Affiliation></AffiliationInfo><AffiliationInfo><Affiliation>Key Laboratory of Integrated Management of Crop Diseases and Pests (Ministry of Education), College of Plant Protection, Nanjing Agricultural University, Nanjing 210095, China.</Affiliation></AffiliationInfo><AffiliationInfo><Affiliation>The Key Laboratory of Plant Immunity, Nanjing Agricultural University, 210095 Nanjing, China.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Ye</LastName><ForeName>Wenwu</ForeName><Initials>W</Initials><Identifier Source="ORCID">https://orcid.org/0000-0001-7347-8935</Identifier><AffiliationInfo><Affiliation>Department of Plant Pathology, Nanjing Agricultural University, 210095 Nanjing, China.</Affiliation></AffiliationInfo><AffiliationInfo><Affiliation>Key Laboratory of Integrated Management of Crop Diseases and Pests (Ministry of Education), College of Plant Protection, Nanjing Agricultural University, Nanjing 210095, China.</Affiliation></AffiliationInfo><AffiliationInfo><Affiliation>The Key Laboratory of Plant Immunity, Nanjing Agricultural University, 210095 Nanjing, China.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Wang</LastName><ForeName>Yan</ForeName><Initials>Y</Initials><AffiliationInfo><Affiliation>Department of Plant Pathology, Nanjing Agricultural University, 210095 Nanjing, China.</Affiliation></AffiliationInfo><AffiliationInfo><Affiliation>Key Laboratory of Integrated Management of Crop Diseases and Pests (Ministry of Education), College of Plant Protection, Nanjing Agricultural University, Nanjing 210095, China.</Affiliation></AffiliationInfo><AffiliationInfo><Affiliation>The Key Laboratory of Plant Immunity, Nanjing Agricultural University, 210095 Nanjing, China.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Wang</LastName><ForeName>Yiming</ForeName><Initials>Y</Initials><AffiliationInfo><Affiliation>Department of Plant Pathology, Nanjing Agricultural University, 210095 Nanjing, China.</Affiliation></AffiliationInfo><AffiliationInfo><Affiliation>Key Laboratory of Integrated Management of Crop Diseases and Pests (Ministry of Education), College of Plant Protection, Nanjing Agricultural University, Nanjing 210095, China.</Affiliation></AffiliationInfo><AffiliationInfo><Affiliation>The Key Laboratory of Plant Immunity, Nanjing Agricultural University, 210095 Nanjing, China.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Dong</LastName><ForeName>Suomeng</ForeName><Initials>S</Initials><Identifier Source="ORCID">https://orcid.org/0000-0002-9623-6776</Identifier><AffiliationInfo><Affiliation>Department of Plant Pathology, Nanjing Agricultural University, 210095 Nanjing, China.</Affiliation></AffiliationInfo><AffiliationInfo><Affiliation>Key Laboratory of Integrated Management of Crop Diseases and Pests (Ministry of Education), College of Plant Protection, Nanjing Agricultural University, Nanjing 210095, China.</Affiliation></AffiliationInfo><AffiliationInfo><Affiliation>The Key Laboratory of Plant Immunity, Nanjing Agricultural University, 210095 Nanjing, China.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Tyler</LastName><ForeName>Brett M</ForeName><Initials>BM</Initials><Identifier Source="ORCID">https://orcid.org/0000-0003-1549-2987</Identifier><AffiliationInfo><Affiliation>Center for Genome Research and Biocomputing, Oregon State University, Corvallis, OR 97331.</Affiliation></AffiliationInfo><AffiliationInfo><Affiliation>Department of Botany and Plant Pathology, Oregon State University, Corvallis, OR 97331.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Wang</LastName><ForeName>Yuanchao</ForeName><Initials>Y</Initials><AffiliationInfo><Affiliation>Department of Plant Pathology, Nanjing Agricultural University, 210095 Nanjing, China; wangyc@njau.edu.cn.</Affiliation></AffiliationInfo><AffiliationInfo><Affiliation>Key Laboratory of Integrated Management of Crop Diseases and Pests (Ministry of Education), College of Plant Protection, Nanjing Agricultural University, Nanjing 210095, China.</Affiliation></AffiliationInfo><AffiliationInfo><Affiliation>The Key Laboratory of Plant Immunity, Nanjing Agricultural University, 210095 Nanjing, China.</Affiliation></AffiliationInfo></Author></AuthorList><Language>eng</Language><PublicationTypeList><PublicationType UI="D016428">Journal Article</PublicationType></PublicationTypeList><ArticleDate DateType="Electronic"><Year>2020</Year><Month>10</Month><Day>20</Day></ArticleDate></Article><MedlineJournalInfo><Country>United States</Country><MedlineTA>Proc Natl Acad Sci U S A</MedlineTA><NlmUniqueID>7505876</NlmUniqueID><ISSNLinking>0027-8424</ISSNLinking></MedlineJournalInfo><CitationSubset>IM</CitationSubset><KeywordList Owner="NOTNLM"><Keyword MajorTopicYN="N">N-glycosylation</Keyword><Keyword MajorTopicYN="N">P. sojae</Keyword><Keyword MajorTopicYN="N">apoplast</Keyword><Keyword MajorTopicYN="N">aspartic protease</Keyword><Keyword MajorTopicYN="N">immunity</Keyword></KeywordList><CoiStatement>The authors declare no competing interest.</CoiStatement></MedlineCitation><PubmedData><History><PubMedPubDate 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sort="Guo, Baodian" uniqKey="Guo B" first="Baodian" last="Guo">Baodian Guo</name><name sortKey="Jiang, Haibin" sort="Jiang, Haibin" uniqKey="Jiang H" first="Haibin" last="Jiang">Haibin Jiang</name><name sortKey="Jiang, Haibin" sort="Jiang, Haibin" uniqKey="Jiang H" first="Haibin" last="Jiang">Haibin Jiang</name><name sortKey="Jiang, Haibin" sort="Jiang, Haibin" uniqKey="Jiang H" first="Haibin" last="Jiang">Haibin Jiang</name><name sortKey="Lin, Yachun" sort="Lin, Yachun" uniqKey="Lin Y" first="Yachun" last="Lin">Yachun Lin</name><name sortKey="Lin, Yachun" sort="Lin, Yachun" uniqKey="Lin Y" first="Yachun" last="Lin">Yachun Lin</name><name sortKey="Lin, Yachun" sort="Lin, Yachun" uniqKey="Lin Y" first="Yachun" last="Lin">Yachun Lin</name><name sortKey="Ma, Zhenchuan" sort="Ma, Zhenchuan" uniqKey="Ma Z" first="Zhenchuan" last="Ma">Zhenchuan Ma</name><name sortKey="Ma, Zhenchuan" sort="Ma, Zhenchuan" uniqKey="Ma Z" first="Zhenchuan" last="Ma">Zhenchuan Ma</name><name sortKey="Ma, Zhenchuan" sort="Ma, Zhenchuan" uniqKey="Ma Z" first="Zhenchuan" last="Ma">Zhenchuan Ma</name><name sortKey="Qiu, Min" sort="Qiu, Min" uniqKey="Qiu M" first="Min" last="Qiu">Min Qiu</name><name sortKey="Qiu, Min" sort="Qiu, Min" uniqKey="Qiu M" first="Min" last="Qiu">Min Qiu</name><name sortKey="Qiu, Min" sort="Qiu, Min" uniqKey="Qiu M" first="Min" last="Qiu">Min Qiu</name><name sortKey="Shu, Haidong" sort="Shu, Haidong" uniqKey="Shu H" first="Haidong" last="Shu">Haidong Shu</name><name sortKey="Shu, Haidong" sort="Shu, Haidong" uniqKey="Shu H" first="Haidong" last="Shu">Haidong Shu</name><name sortKey="Shu, Haidong" sort="Shu, Haidong" uniqKey="Shu H" first="Haidong" last="Shu">Haidong Shu</name><name sortKey="Sun, Liang" sort="Sun, Liang" uniqKey="Sun L" first="Liang" last="Sun">Liang Sun</name><name sortKey="Sun, Liang" sort="Sun, Liang" uniqKey="Sun L" first="Liang" last="Sun">Liang Sun</name><name sortKey="Sun, Liang" sort="Sun, Liang" uniqKey="Sun L" first="Liang" last="Sun">Liang Sun</name><name sortKey="Wang, Yan" sort="Wang, Yan" uniqKey="Wang Y" first="Yan" last="Wang">Yan Wang</name><name sortKey="Wang, Yan" sort="Wang, Yan" uniqKey="Wang Y" first="Yan" last="Wang">Yan Wang</name><name sortKey="Wang, Yan" sort="Wang, Yan" uniqKey="Wang Y" first="Yan" last="Wang">Yan Wang</name><name sortKey="Wang, Yiming" sort="Wang, Yiming" uniqKey="Wang Y" first="Yiming" last="Wang">Yiming Wang</name><name sortKey="Wang, Yiming" sort="Wang, Yiming" uniqKey="Wang Y" first="Yiming" last="Wang">Yiming Wang</name><name sortKey="Wang, Yiming" sort="Wang, Yiming" uniqKey="Wang Y" first="Yiming" last="Wang">Yiming Wang</name><name sortKey="Wang, Yuanchao" sort="Wang, Yuanchao" uniqKey="Wang Y" first="Yuanchao" last="Wang">Yuanchao Wang</name><name sortKey="Wang, Yuanchao" sort="Wang, Yuanchao" uniqKey="Wang Y" first="Yuanchao" last="Wang">Yuanchao Wang</name><name sortKey="Wang, Yuanchao" sort="Wang, Yuanchao" uniqKey="Wang Y" first="Yuanchao" last="Wang">Yuanchao Wang</name><name sortKey="Xia, Yeqiang" sort="Xia, Yeqiang" uniqKey="Xia Y" first="Yeqiang" last="Xia">Yeqiang Xia</name><name sortKey="Xia, Yeqiang" sort="Xia, Yeqiang" uniqKey="Xia Y" first="Yeqiang" last="Xia">Yeqiang Xia</name><name sortKey="Xiao, Junhua" sort="Xiao, Junhua" uniqKey="Xiao J" first="Junhua" last="Xiao">Junhua Xiao</name><name sortKey="Xiao, Junhua" sort="Xiao, Junhua" uniqKey="Xiao J" first="Junhua" last="Xiao">Junhua Xiao</name><name sortKey="Xiao, Junhua" sort="Xiao, Junhua" uniqKey="Xiao J" first="Junhua" last="Xiao">Junhua Xiao</name><name sortKey="Xuan, Mingrun" sort="Xuan, Mingrun" uniqKey="Xuan M" first="Mingrun" last="Xuan">Mingrun Xuan</name><name sortKey="Xuan, Mingrun" sort="Xuan, Mingrun" uniqKey="Xuan M" first="Mingrun" last="Xuan">Mingrun Xuan</name><name sortKey="Xuan, Mingrun" sort="Xuan, Mingrun" uniqKey="Xuan M" first="Mingrun" last="Xuan">Mingrun Xuan</name><name sortKey="Ye, Wenwu" sort="Ye, Wenwu" uniqKey="Ye W" first="Wenwu" last="Ye">Wenwu Ye</name><name sortKey="Ye, Wenwu" sort="Ye, Wenwu" uniqKey="Ye W" first="Wenwu" last="Ye">Wenwu Ye</name><name sortKey="Ye, Wenwu" sort="Ye, Wenwu" uniqKey="Ye W" first="Wenwu" last="Ye">Wenwu Ye</name><name sortKey="Zhang, Baiyu" sort="Zhang, Baiyu" uniqKey="Zhang B" first="Baiyu" last="Zhang">Baiyu Zhang</name><name sortKey="Zhang, Baiyu" sort="Zhang, Baiyu" uniqKey="Zhang B" first="Baiyu" last="Zhang">Baiyu Zhang</name><name sortKey="Zhang, Baiyu" sort="Zhang, Baiyu" uniqKey="Zhang B" first="Baiyu" last="Zhang">Baiyu Zhang</name><name sortKey="Zhang, Qi" sort="Zhang, Qi" uniqKey="Zhang Q" first="Qi" last="Zhang">Qi Zhang</name><name sortKey="Zhang, Qi" sort="Zhang, Qi" uniqKey="Zhang Q" first="Qi" last="Zhang">Qi Zhang</name><name sortKey="Zhang, Qi" sort="Zhang, Qi" uniqKey="Zhang Q" first="Qi" last="Zhang">Qi Zhang</name></country><country name="États-Unis"><region name="Oregon"><name sortKey="Tyler, Brett M" sort="Tyler, Brett M" uniqKey="Tyler B" first="Brett M" last="Tyler">Brett M. Tyler</name></region><name sortKey="Tyler, Brett M" sort="Tyler, Brett M" uniqKey="Tyler B" first="Brett M" last="Tyler">Brett M. Tyler</name></country></tree></affiliations></record>Pour manipuler ce document sous Unix (Dilib)
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